The Role of Vial Surface Treatment in Minimizing Analyte Adsorption and Loss
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Achieving Maximum Protein and Peptide Recovery, Sensitivity
moderately basic analyte, instead of using a glass container that has a high surface silanol activity. For more strongly basic analytes, a polypropylene container with a pure hydrocarbon surface would work better than deactivated glass containers. Some proteins and peptides bind to glass surfaces via ionic
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Adsorption Phenomenon and Development of Low Adsorption Vials
1) The low-adsorption glass vials (LabTotal vials) inhibit the adsorption of basic compounds. 2) The low-adsorption PP vials (TORAST-H TM Bio vials) inhibit the adsorption of peptides. These low-adsorption vials are expected to help ensure the reliability of high-sensitivity analysis.
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Improving LC/MS/MS-based bioanalytical method - ScienceDirect
Aug 1, 2021 · For an analysis of compounds which are susceptible to metal adsorption, ideally a system suitability test would be performed to ensure there will not be any sample loss or detrimental peak shape effects resulting from potential analyte-to-metal interactions.
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Investigation of Fogging Behavior in a Lyophilized Drug
Mar 1, 2019 · The glass surface can be influenced by additional factors such as washing conditions or depyrogenation treatment. 19 Our experiments demonstrated a lesser extent of fogging for unwashed vials and washed/air-dried vials compared to the depyrogenated vials (depyrogenation temperature of 250°C), in line with the observation reported by Abdul
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2ml amber and clear hplc vials for sale-Aijiren HPLC Vials
Advances and applications of nanophotonic biosensors – Nature Jan 17, 2022 · The simplest model for an analyte–receptor interaction is 1:1 binding, in which the surface concentration of the analyte–receptor complex, R, is expressed as: dR(t)/dt = k a C[R max − R(t The Effect of Sample Vials on Analyte Stability: Mitigating reported
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Aijiren.com/chem/sampleprep SAMPLE PREPARATION Aijiren.com
or into an ICP-MS/atomic adsorption source, or into a cuvette or NMR tube for further characterization. The aim of sample preparation is to provide a sample aliquot that (a) is relatively free of interferences, (b) will not damage the column or instrument and (c) is compatible with the intended analytical method.
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(PDF) The role of methanol addition to water samples in
Feb 23, 2015 · The role of methanol addition to water samples in reducing analyte adsorption and matrix effects in liquid chromatography-tandem mass spectrometry February 2015 Journal of Chromatography A 1389
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Journal of Chromatography A - ResearchGate
Analyte adsorption was greatest at acidic pH due to the positive charge on the metal oxide surface. Analyte recovery increased when a series of injections was performed; this effect is known as
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Preservation Technique - an overview | ScienceDirect Topics
The active sites on the inner wall surface of PE bottles (such as hydrocarbon radicals and carbonyl groups) and additives (amine, thiol, sulfide, or phenolic groups) can cause analyte loss by adsorption and reduction. In general, adsorptive loss for PTFE appears lower than for Pyrex glass.
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The role of methanol addition to water samples in reducing
Apr 10, 2015 · During the preparation and detection process, any experimental apparatus in contact with analytes may cause surface adsorption, including: storage containers, pipette tips, microfiltration membrane filters, and sample vials, as well as sample flow path and sample loop [14], [16], [17], [18]. Therefore, it is important to assess and eliminate
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Plasma Polymerized HMDSO Coatings For Syringes To Minimize
Apr 1, 2021 · Uncoated glass disc samples were used as controls. Adsorption and retention data were reported in ng/cm 2. Statistical Analysis. The effect of surface coating and pH on protein adsorption and retention, both in the presence and absence of PS80, was analyzed using two-way ANOVA followed by post-hoc Tukey's comparison test.
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The Role of Vial Surface Treatment in Minimizing Analyte
The Role of Vial Surface Treatment in Minimizing Analyte Adsorption andSample Loss Advances and applications of nanophotonic biosensors - Nature Jan 17, 2022 · The simplest model for an analyte–receptor interaction is 1:1 binding, in which the surface concentration of the analyte–receptor complex, R, is expressed as: dR(t)/dt = k a C[R max
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Overcoming Glass Vial Adsorption Effects for Trace Analysis
Purpose: To evaluate the adsorption effect of a typical basic drug on the surface of glass autosampler vials. Method: Nortriptyline was chosen as a model compound to demonstrate the adsorption effect. The adsorption of this compound in autosampler vials was monitored using LC/MS/MS analysis.
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Surface Modification, Methods | SpringerLink
Surface modification techniques can be used to alter the wettability behavior of microfluidic devices. This difference in wettability can be used to control the flow rate in devices. There are many other benefits of hydrophilic surface treatments, including the ability to increase adhesion and capillary effects [ 2 ].
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